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Molfinity

GDC-0349 - CAS 1207360-89-1

GDC-0349 - CAS 1207360-89-1

SKU:MF-0000286-01

Regular price $34.67 USD
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  • Bioactivity

    GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.

  • Target

    PI3K, Autophagy, mTOR

  • Related Pathways

    Autophagy, PI3K/Akt/mTOR signaling

  • CAS Number

    1207360-89-1

  • Purity

    0.9898

  • Molecular Formula

    C24H32N6O3

  • Molecular Weight

    452.55

  • SMILES

    CCNC(=O)Nc1ccc(cc1)-c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound