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GDC-0349 - CAS 1207360-89-1
GDC-0349 - CAS 1207360-89-1
SKU:MF-0000286-01
Regular price
$34.67 USD
Regular price
$21.45 USD
Sale price
$34.67 USD
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Product Details
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Bioactivity
GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
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Target
PI3K, Autophagy, mTOR
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Related Pathways
Autophagy, PI3K/Akt/mTOR signaling
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CAS Number
1207360-89-1
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Purity
0.9898
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Molecular Formula
C24H32N6O3
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Molecular Weight
452.55
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SMILES
CCNC(=O)Nc1ccc(cc1)-c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound