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GDC-2394 sodium salt - CAS 2238822-08-5

GDC-2394 sodium salt - CAS 2238822-08-5

MF-0098424-01

$221.11 USD
$221.11 USD
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Product Details

  • Bioactivity

    GDC-2394 sodium salt is an orally active selective NLRP3 inhibitor that concurrently inhibits IL-1β with IC50 values of 0.4 μM (human) and 0.1 μM (mouse) . This compound specifically inhibits NLRP3-induced caspase-1 activity without affecting NLRC4-dependent inflammasome activation.

  • Target

    IL Receptor, NOD

  • Related Pathways

    NF-κB, Immunology/Inflammation

  • CAS Number

    2238822-08-5

  • Purity

    0.995

  • Molecular Formula

    C20H24N5NaO4S

  • Molecular Weight

    453.49

  • SMILES

    [Na+].CN[C@@H]1COC2=C(C=NN2C1)S(=O)(=O)[N-]C(=O)NC1=C2CCCC2=CC2=C1CCC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound