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Molfinity

Gefapixant - CAS 1015787-98-0

Gefapixant - CAS 1015787-98-0

SKU:MF-0109263-01

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  • Bioactivity

    Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.

  • Target

    P2X Receptor

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience

  • CAS Number

    1015689

  • Purity

    0.9972

  • Molecular Formula

    C14H19N5O4S

  • Molecular Weight

    353.4

  • SMILES

    COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound