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Gefitinib-d6 - CAS 1228664-49-0
Gefitinib-d6 - CAS 1228664-49-0
SKU:MF-0102207-01
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Product Details
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Bioactivity
Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM) .
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Target
Autophagy, EGFR
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Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
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CAS Number
1228664-49-0
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Molecular Formula
C22H18D6ClFN4O3
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Molecular Weight
452.94
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SMILES
C1C2C(=C(N=CN=2)NC2C=CC(F)=C(Cl)C=2)C=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])N2CCOCC2)C=1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Isotope products