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Gefitinib-d6 - CAS 1228664-49-0

Gefitinib-d6 - CAS 1228664-49-0

SKU:MF-0102207-01

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  • Bioactivity

    Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM) .

  • Target

    Autophagy, EGFR

  • Related Pathways

    Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

  • CAS Number

    1228664-49-0

  • Molecular Formula

    C22H18D6ClFN4O3

  • Molecular Weight

    452.94

  • SMILES

    C1C2C(=C(N=CN=2)NC2C=CC(F)=C(Cl)C=2)C=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])N2CCOCC2)C=1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Isotope products