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GEM144 - CAS 2487526-28-1

GEM144 - CAS 2487526-28-1

MF-0000438-01

$1,927.85 USD
$1,391.00 USD $1,927.85 USD
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Product Details

  • Bioactivity

    GEM144 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, blocks the cell cycle in G1/S phase and induces apoptosis.

  • Target

    Apoptosis, Others, DNA/RNA Synthesis, HDAC

  • Related Pathways

    Others, Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis

  • CAS Number

    2487526-28-1

  • Molecular Formula

    C28H31NO5

  • Molecular Weight

    461.55

  • SMILES

    O(C(C(NO)=O)C)C1=C(C23CC4CC(C2)CC(C3)C4)C=C(C=C1)C5=CC=C(/C=C/C(O)=O)C=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound