Geninthiocin A - CAS 158792-27-9

Geninthiocin A is a cyclic thiopeptide bacterial metabolite originally isolated from Streptomyces sp. DD84. It is active against a variety of Gram-positive bacteria (MICs = 0.2-4 μg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 μg/ml), and the fungus M. hiemalis (MIC = 38 μg/ml) . Geninthiocin A also induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml.

Others, Antifungal, Antibacterial

Others, Microbiology/Virology

158756

C50H49N15O15S

1132.09

[H][C@]1(NC(=O)c2csc(n2)-c2ccc(nc2-c2coc(n2)C(=C)NC(=O)C(=C)NC(=O)c2nc(oc2C)C(=C)NC(=O)[C@@H](NC(=O)C(=C)NC(=O)c2coc(n2)\C(NC1=O)=C\C)C(C)(C)O)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)[C@@H](C)O

-20°C

Ice Packs

Small Compound