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Molfinity

Getagozumab - CAS 2642374-04-5

Getagozumab - CAS 2642374-04-5

MF-0101356-01

$221.11 USD
$221.11 USD
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Product Details

  • Bioactivity

    Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.

  • Target

    Endothelin Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    2642374-04-5

  • Purity

    0.989

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Inhibitory Antibodies