Molfinity
GeX-2 - CAS 2900996-95-2
GeX-2 - CAS 2900996-95-2
SKU:MF-0126824-01
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Product Details
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Bioactivity
GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.
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Target
AChR, GABA Receptor, Calcium Channel
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Related Pathways
Neuroscience, Metabolism, Membrane transporter/Ion channel
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CAS Number
2900996-95-2
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Molecular Formula
C103H169N43O27
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Molecular Weight
2441.72
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SMILES
C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N)=O)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(O)=O)=O)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)=O)CCCNC(=N)N)=O)CO)=O)CCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide