GGFG-PAB-MMAE - CAS 3049886-19-0

GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC that comprises an ADC linker (GGFG-PAB) and the potent tubulin polymerization inhibitor, MMAE. This formulation combines the targeted delivery mechanism inherent in ADC technology with the effective inhibitory action of MMAE against tubulin polymerization.

Drug-Linker Conjugates for ADC, Microtubule Associated

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

3049867

C62H92N10O13

1185.45

[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)C=C3)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

-20°C

Ice Packs

Small Compound