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GGTI-2418 - CAS 501010-06-6
GGTI-2418 - CAS 501010-06-6
SKU:MF-0022398-01
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$45.88 USD
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Product Details
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Bioactivity
GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), exhibiting inhibitory activities with IC50 values of 9.5 nM for GGTase I and 53 μM for FTase, respectively. Additionally, it enhances p27 (Kip1) expression and induces significant regression of breast tumors.
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Target
Apoptosis, Transferase
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Related Pathways
Apoptosis, Metabolism
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CAS Number
501010-06-6
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Purity
0.9918
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Molecular Formula
C23H31N5O4
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Molecular Weight
441.52
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SMILES
CC(C)C[C@H](NC(=O)N1CCN(Cc2nc[nH]c2C)C(=O)[C@@H]1Cc1ccccc1)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound