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GGTI-286 - CAS 171744-11-9

GGTI-286 - CAS 171744-11-9

MF-0139716-01

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Product Details

  • Bioactivity

    GGTI-286 is a potent, cell permeable GGTase I inhibitor (IC50: 2 μM) . GGTI-286 inhibits Rap1A geranylation in NIH3T3 cells (IC50: 2 μM) more potently than H-Ras farnesylation (IC50>30 μM) . Ras4B stimulation (IC50: 1 μM) .

  • Target

    Others, Ras

  • Related Pathways

    Others, MAPK, GPCR/G Protein

  • CAS Number

    171724

  • Molecular Formula

    C23H31N3O3S

  • Molecular Weight

    429.58

  • SMILES

    C(N[C@H](C(OC)=O)CC(C)C)(=O)C1=C(C=C(NC[C@H](CS)N)C=C1)C2=CC=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound