Molfinity

GGTI-286 hydrochloride - CAS 181141-66-2

SKU:MF-0140786-01

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Product Details

Bioactivity
GGTI-286 hydrochloride is a potent inhibitor of GGTase I (IC50: 2 μM) and is also effective in inhibiting K-Ras4B (IC50: 1 μM) . farnesylation (IC50=2 and >30 μM) .
Target
Others, Ras
Related Pathways
Others, GPCR/G Protein, MAPK
CAS Number
181073
Molecular Formula
C23H32ClN3O3S
Molecular Weight
466.04
SMILES
Cl.COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound