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GGTI298 - CAS 180977-44-0

GGTI298 - CAS 180977-44-0

MF-0022399-01

$1,647.05 USD
$1,183.00 USD $1,647.05 USD
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Product Details

  • Bioactivity

    GGTI298, a CAAZ peptidomimetic and potent geranylgeranyltransferase I (GGTase I) inhibitor, efficiently blocks the processing of geranylgeranylated Rap1A while exerting minimal impact on the processing of farnesylated Ha-Ras. The inhibitor displays in vivo IC50 values of 3 μM for Rap1A and >20 μM for Ha-Ras, respectively.

  • Target

    Apoptosis, Others

  • Related Pathways

    Others, Apoptosis

  • CAS Number

    180977-44-0

  • Molecular Formula

    C27H33N3O3S

  • Molecular Weight

    479.63

  • SMILES

    C(N[C@H](C(OC)=O)CC(C)C)(=O)C1=C(C=C(NC[C@H](CS)N)C=C1)C=2C3=C(C=CC2)C=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound