GHP-88309 - CAS 1269267-87-9

GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.

DNA/RNA Synthesis, RSV

Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

1269171

C16H11FN2O

266.27

O=C(N)C1=C(F)C=CC=C1C2=CC=CC=3C=NC=CC32

-20°C

Ice Packs

Small Compound