Gilteritinib - CAS 1254053-43-4

Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively) . In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia.

C-Kit, FLT, TAM Receptor

Tyrosine Kinase/Adaptors, Angiogenesis

1254006

0.999

C29H44N8O3

552.71

CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1

-20°C

Ice Packs

Small Compound