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Giredestrant - CAS 1953133-47-5
Giredestrant - CAS 1953133-47-5
SKU:MF-0016232-01
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$116.81 USD
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$116.81 USD
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Product Details
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Bioactivity
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.
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Target
Estrogen Receptor/ERR, Estrogen/progestogen Receptor
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Related Pathways
Endocrinology/Hormones
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CAS Number
1953081
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Purity
0.9956
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Molecular Formula
C27H31F5N4O
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Molecular Weight
522.55
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SMILES
C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound