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Molfinity

GK563 - CAS 2351820-19-2

GK563 - CAS 2351820-19-2

MF-0098719-01

$345.72 USD
$345.72 USD
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Product Details

  • Bioactivity

    GK563, a selective Ca 2+-independent phospholipase A2 (GVIA iPLA2) inhibitor, exhibits a potent IC50 value of 1 nM and demonstrates 22,000-fold greater activity against GVIA iPLA2 compared to GIVA cPLA2. Its efficacy in reducing β-cell apoptosis triggered by proinflammatory cytokines suggests potential therapeutic benefits in combating autoimmune disorders, including type 1 diabetes.

  • Target

    Phospholipase, Apoptosis, Others

  • Related Pathways

    Others, Metabolism, Apoptosis

  • CAS Number

    2351799

  • Molecular Formula

    C16H22O2

  • Molecular Weight

    246.34

  • SMILES

    C(CC)[C@H]1[C@H](CCCCC2=CC=CC=C2)C(=O)O1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound