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Molfinity

GKI-1 - CAS 2444764-03-6

GKI-1 - CAS 2444764-03-6

MF-0022405-01

$97.31 USD
$97.31 USD
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Product Details

  • Bioactivity

    GKI-1 is a Greatwall (GWL) kinase inhibitor with an IC50 of 4.9 for hGWLFL and 2.5 μM for hGWL-KinDom. It exhibits stronger inhibition on ROCK1 with an IC50 of 11 μM and only weakly inhibits PKA.

  • Target

    ROCK, Others

  • Related Pathways

    Stem Cells, Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling

  • CAS Number

    2444764-03-6

  • Purity

    0.9996

  • Molecular Formula

    C15H12ClN3

  • Molecular Weight

    269.73

  • SMILES

    N(C=1C=C(C=CC1)C=2C=NNC2)C3=CC=C(Cl)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound