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Molfinity

Glasdegib - CAS 1095173-27-5

Glasdegib - CAS 1095173-27-5

SKU:MF-0017425-01

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  • Bioactivity

    Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.

  • Target

    Smo, Hedgehog/Smoothened

  • Related Pathways

    GPCR/G Protein, Stem Cells

  • CAS Number

    1095141

  • Purity

    0.9872

  • Molecular Formula

    C21H22N6O

  • Molecular Weight

    374.44

  • SMILES

    CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound