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Glecirasib - CAS 2657613-87-9
Glecirasib - CAS 2657613-87-9
SKU:MF-0099707-01
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Product Details
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Bioactivity
Glecirasib (JAB-21822) is an orally active KRAS G12C inhibitor that selectively binds to and inhibits the activity of KRAS G12C mutants, thereby inhibiting KRAS G12C-dependent signaling. In animal models, KRAS G12C inhibitor 36 showed a favorable safety profile and potential to inhibit tumor growth.
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Target
Kras, Ras
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Related Pathways
MAPK, GPCR/G Protein
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CAS Number
2657517
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Purity
>99.99%
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Molecular Formula
C31H26ClF4N7O2
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Molecular Weight
640.03
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SMILES
N#CC=1C(=O)N(C=2N=C(C(Cl)=CC2C1N3CCN(C(=O)C=C)CC3)C=4C(F)=C(F)C(F)=C(F)C4N)C=5C(=NC=CC5C)C(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound