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Glecirasib - CAS 2657613-87-9

Glecirasib - CAS 2657613-87-9

SKU:MF-0099707-01

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  • Bioactivity

    Glecirasib (JAB-21822) is an orally active KRAS G12C inhibitor that selectively binds to and inhibits the activity of KRAS G12C mutants, thereby inhibiting KRAS G12C-dependent signaling. In animal models, KRAS G12C inhibitor 36 showed a favorable safety profile and potential to inhibit tumor growth.

  • Target

    Kras, Ras

  • Related Pathways

    MAPK, GPCR/G Protein

  • CAS Number

    2657517

  • Purity

    >99.99%

  • Molecular Formula

    C31H26ClF4N7O2

  • Molecular Weight

    640.03

  • SMILES

    N#CC=1C(=O)N(C=2N=C(C(Cl)=CC2C1N3CCN(C(=O)C=C)CC3)C=4C(F)=C(F)C(F)=C(F)C4N)C=5C(=NC=CC5C)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound