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GLI1-IN-1 - CAS 2923907-92-8
GLI1-IN-1 - CAS 2923907-92-8
SKU:MF-0120666-01
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Product Details
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Bioactivity
GLI1-IN-1 (CBC-1), a GLI-1 inhibitor, exhibits superior water solubility and anticancer properties. It effectively induces apoptosis and inhibits colorectal cancer growth by targeting the Hedgehog (HH) pathway (IC 50 = 1.3 μM) [1].
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Target
Apoptosis, Hedgehog/Smoothened
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Related Pathways
Apoptosis, GPCR/G Protein, Stem Cells
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CAS Number
2923907-92-8
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Molecular Formula
C42H60N2O9
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Molecular Weight
736.93
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SMILES
C[C@@]12[C@@](O)([C@@]3(O)[C@](C[C@H]1OC(/C=C/C4=CC=CC=C4)=O)([C@]5(C)C(=CC3)C[C@@H](OC(CN6CCN(C)CC6)=O)CC5)[H])CC[C@]2([C@@H](OC([C@H](CC)C)=O)C)O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound