GLP-1 (9-36) amide - CAS 161748-29-4

GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor. GLP-1 (9-36) amide potently inhibits hepatic glucose production (HGP) and is a weak insulinotropic agent.

Glucagon Receptor

GPCR/G Protein

161715

0.97

C140H214N36O43

3089.41

CC[C@H](C)[C@@H](C(N[C@@H](C)C(N[C@@H](Cc1c[nH]c2c1cccc2)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](Cc1ccccc1)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(N)=O)NC(CNC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](Cc(cc1)ccc1O)NC([C@H](CO)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)O)NC([C@H](Cc1ccccc1)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CCC(O)=O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

-20°C

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