GLP-1R agonist 32 - CAS 3047875-57-7

GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.

Glucagon Receptor

GPCR/G Protein

3047811

C32H31ClFN3O5

592.06

C(N1C=2C(N=C1CN3CCC(CC3)C4=C5C(O[C@@H](CO5)C6=CC=C(Cl)C=C6)=CC=C4)=C(F)C=C(C(O)=O)C2)[C@@H]7CCO7

-20°C

Ice Packs

Small Compound