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GLP-1R modulator-1 - CAS 2978244-71-0
GLP-1R modulator-1 - CAS 2978244-71-0
SKU:MF-0117897-01
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Product Details
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Bioactivity
GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R) . It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH) .
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Target
Glucagon Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
2978173
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Molecular Formula
C41H38ClFN6O4
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Molecular Weight
733.23
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SMILES
C[C@]1(OC=2C(O1)=CC=CC2C=3CCN(CC=4N(C[C@@H]5CCO5)C=6C(N4)=CC(NC(=O)C=7C=C8C(=C(C)C7)NN=C8C)=CC6)CC3)C9=C(F)C=C(Cl)C=C9
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound