GLS1 Inhibitor - CAS 1832646-52-2

GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM) .1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro (GI50= 0.011 μM) . GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model.

Others, Glutaminase

Proteases/Proteasome, Others

1832592

C19H21N7O2S

411.48

N([C@H]1CN(CC1)C2=CC=CN=N2)C=3SC(NC([C@@H](OC)C4=CC=CC=C4)=O)=NN3

-20°C

Ice Packs

Small Compound