(Glu2) -TRH - CAS 85541-78-2

(Glu2) -TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH), acts as a negative modulator of TRH's cholinergic effect in the mouse brain, significantly reducing TRH-induced release of extracellular acetylcholine in the hippocampus. Resistant to metabolism by thyroliberinase, (Glu2) -TRH exhibits neuroprotective, antidepressant, and anticonvulsant properties in the CNS [1].

Thyroid hormone receptor (THR), Endogenous Metabolite

Metabolism, Endocrinology/Hormones

85461

C15H22N4O6

354.36

NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)N1

-20°C

Ice Packs

Peptide