Glucocorticoid receptor agonist-2 - CAS 2166378-92-1

Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist with an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1] and is instrumental in the synthesis of anti-inflammatory ADC molecules.

ADC Cytotoxin, Glucocorticoid Receptor

Antibody-drug Conjugate/ADC Related, Endocrinology/Hormones

2166285

C34H35F2NO7

607.64

C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)C4=CC=C(OC5=CC(N)=CC=C5)C=C4)[H])([C@]6([C@](F)([C@@H](O)C3)[C@]7(C)C([C@@H](F)C6)=CC(=O)C=C7)[H])[H]

-20°C

Ice Packs

Small Compound