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Glucosylceramide synthase-IN-1 - CAS 2601393-20-6
Glucosylceramide synthase-IN-1 - CAS 2601393-20-6
SKU:MF-0153081-01
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$1,164.42 USD
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Product Details
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Bioactivity
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor, acting on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM), and can be used to study Gaucher disease.
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Target
Others, Transferase
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Related Pathways
Others, Metabolism
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CAS Number
2601367
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Molecular Formula
C24H20F4N2O3
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Molecular Weight
460.42
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SMILES
CC(C)(O)c1ccc(cc1)N1Cc2c(ccnc2-c2ccc(F)cc2OCC(F)(F)F)C1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound