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Glucosylceramide synthase-IN-1 - CAS 2601393-20-6

Glucosylceramide synthase-IN-1 - CAS 2601393-20-6

SKU:MF-0153081-01

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  • Bioactivity

    Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor, acting on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM), and can be used to study Gaucher disease.

  • Target

    Others, Transferase

  • Related Pathways

    Others, Metabolism

  • CAS Number

    2601367

  • Molecular Formula

    C24H20F4N2O3

  • Molecular Weight

    460.42

  • SMILES

    CC(C)(O)c1ccc(cc1)N1Cc2c(ccnc2-c2ccc(F)cc2OCC(F)(F)F)C1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound