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Glucosylceramide synthase-IN-2 - CAS 2597958-02-4

Glucosylceramide synthase-IN-2 - CAS 2597958-02-4

MF-0039860-01

$1,471.55 USD
$1,471.55 USD
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Product Details

  • Bioactivity

    Glucosylceramide synthase-IN-2 (compound T-690) is a potent, blood-brain barrier-permeable, orally active inhibitor of glucosylceramide synthase (GCS), with IC50 values of 15 nM for human GCS and 190 nM for mouse GCS. It exhibits non-competitive inhibition of C8 ceramide and UDP glucose.

  • Target

    Others, Transferase

  • Related Pathways

    Metabolism, Others

  • CAS Number

    2597958-02-4

  • Molecular Formula

    C22H20F3N3O4

  • Molecular Weight

    447.41

  • SMILES

    CC(C)(O)c1ccc(NC(=O)c2ccnn(-c3ccccc3OCC(F)(F)F)c2=O)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound