GLUT-1-IN-4 - CAS 735-16-0

GLUT-1-IN-4 (Compound 13) is an inhibitor of the GLUT-1 glucose transporter that depends on the p53 protein. It suppresses the proliferation of various cancer cells at submicromolar IC50 levels. Additionally, GLUT-1-IN-4 can halt the cell cycle, induce oxidative stress, and promote apoptosis (cell death) .

Apoptosis, Reactive Oxygen Species, transporter

Metabolism, NF-κB, Apoptosis, Immunology/Inflammation

719

C15H10N2O3

266.251

O=[N+](C1=CC=C(C=CC2=C3C=CC=CC3=NC=C2)O1)[O-]

-20°C

Ice Packs

Small Compound