Gly-Cyclopropane-Exatecan - CAS 2414254-49-0

Gly-Cyclopropane-Exatecan, a DNA Topoisomerase I inhibitor containing Exatecan, is key in synthesizing the anti-B7-H4 ADC, specifically the ADC hu2F7-Exatecan (compound 34) . This compound demonstrated antitumor activity both in vivo and in vitro [1].

ADC Cytotoxin, Topoisomerase

DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

2414205

C32H34FN5O7

619.64

CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)C(OCNC(=O)CN)C6CC6)c(c3Cn1c2=O)c45

-20°C

Ice Packs

Small Compound