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Molfinity

GNE-0723 - CAS 1883518-31-7

GNE-0723 - CAS 1883518-31-7

SKU:MF-0032936-01

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  • Bioactivity

    GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD) .

  • Target

    IGluR, NMDAR

  • Related Pathways

    Neuroscience, Membrane transporter/Ion channel

  • CAS Number

    1883480

  • Purity

    0.9991

  • Molecular Formula

    C16H8ClF6N5OS

  • Molecular Weight

    467.78

  • SMILES

    C(F)(F)(F)C1=C(N2C(S1)=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)[C@H]4[C@H](C#N)C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound