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Molfinity

GNE-1858 - CAS 2680616-96-8

GNE-1858 - CAS 2680616-96-8

SKU:MF-0022434-01

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  • Bioactivity

    GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA) .

  • Target

    MAPK

  • Related Pathways

    MAPK

  • CAS Number

    2680512

  • Purity

    0.9936

  • Molecular Formula

    C21H26F2N8

  • Molecular Weight

    428.48

  • SMILES

    CC(C)n1ncc2cnc(Nc3cc(nc(n3)N3CCC(F)(F)C3)C3CCNC3)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound