GNE-2256 - CAS 2102170-43-2

GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.

Others, IRAK

NF-κB, Others, Immunology/Inflammation

2102125

0.9995

C24H27FN6O4

482.51

N(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5

-20°C

Ice Packs

Small Compound