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Molfinity

GNE-490 - CAS 1033739-92-2

GNE-490 - CAS 1033739-92-2

MF-0016881-01

$87.56 USD
$87.56 USD
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Product Details

  • Bioactivity

    GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM) .

  • Target

    PI3K, mTOR

  • Related Pathways

    PI3K/Akt/mTOR signaling

  • CAS Number

    1033645

  • Purity

    0.9977

  • Molecular Formula

    C18H22N6O2S

  • Molecular Weight

    386.47

  • SMILES

    Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2sc(cc2n1)C(C)(C)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound