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Molfinity

GNE-4997 - CAS 1705602-02-3

GNE-4997 - CAS 1705602-02-3

SKU:MF-0032934-01

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  • Bioactivity

    GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM) . The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.

  • Target

    Others, Tyrosine Kinases

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others

  • CAS Number

    1705602-02-3

  • Molecular Formula

    C25H27F2N5O3S

  • Molecular Weight

    515.58

  • SMILES

    C[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C(NC4=CN([C@@H]([C@@]5(S(=O)(=O)CCCC5)[H])C6=CC=CC=C6)N=C4)=O)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound