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GNE-4997 - CAS 1705602-02-3
GNE-4997 - CAS 1705602-02-3
SKU:MF-0032934-01
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$2,436.80 USD
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$2,436.80 USD
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Product Details
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Bioactivity
GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM) . The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.
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Target
Others, Tyrosine Kinases
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Related Pathways
Tyrosine Kinase/Adaptors, Others
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CAS Number
1705602-02-3
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Molecular Formula
C25H27F2N5O3S
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Molecular Weight
515.58
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SMILES
C[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C(NC4=CN([C@@H]([C@@]5(S(=O)(=O)CCCC5)[H])C6=CC=CC=C6)N=C4)=O)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound