GNE-555 - CAS 1428902-71-9

GNE-555, a selective and metabolically stable mTOR inhibitor (K i=1.5 nM), demonstrates good oral bioavailability and antiproliferative activity on PC3 and MCF-7 cells, making it suitable for cancer research [1] [2].

MTOR

PI3K/Akt/mTOR signaling

1428902-71-9

C26H34N6O3

478.59

C[C@@H]1N(C2=C3C([C@@]4(N([C@](C3)(CC4)[H])C5COC5)[H])=NC(=N2)C6=CC=C(NC(NCC)=O)C=C6)CCOC1

-20°C

Ice Packs

Small Compound