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Molfinity

GNE-616 - CAS 2349371-81-7

GNE-616 - CAS 2349371-81-7

SKU:MF-0022435-01

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  • Bioactivity

    GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor [Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7] for the treatment of chronic pain.

  • Target

    Sodium Channel, Others

  • Related Pathways

    Membrane transporter/Ion channel, Others

  • CAS Number

    2349283

  • Molecular Formula

    C24H23F4N5O3S

  • Molecular Weight

    537.53

  • SMILES

    C(F)(F)(F)[C@@H]1C[C@@H](N(CC1)[C@@H]2C=3C(=CC(S(NC=4C=CN=CN4)(=O)=O)=C(F)C3)OCC2)C5=CC=CC=N5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound