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GNE-616 - CAS 2349371-81-7
GNE-616 - CAS 2349371-81-7
SKU:MF-0022435-01
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$2,436.80 USD
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$2,436.80 USD
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Product Details
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Bioactivity
GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor [Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7] for the treatment of chronic pain.
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Target
Sodium Channel, Others
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Related Pathways
Membrane transporter/Ion channel, Others
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CAS Number
2349283
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Molecular Formula
C24H23F4N5O3S
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Molecular Weight
537.53
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SMILES
C(F)(F)(F)[C@@H]1C[C@@H](N(CC1)[C@@H]2C=3C(=CC(S(NC=4C=CN=CN4)(=O)=O)=C(F)C3)OCC2)C5=CC=CC=N5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound