Molfinity

GNE-618 - CAS 1362151-42-5

SKU:MF-0013722-01

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Size 5 mg 1 mL - 10 mM (in DMSO) 25 mg 50 mg 100 mg

Product Details

Bioactivity
GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM) . GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.
Target
NAMPT
Related Pathways
Metabolism
CAS Number
1362104
Molecular Formula
C21H15F3N4O3S
Molecular Weight
460.43
SMILES
FC(F)(F)c1cccc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3[nH]ncc3c2)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound