GNE684 - CAS 2438637-64-8

GNE684 is a potent inhibitor of receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM for human, 189 nM for mouse, and 691 nM for rat RIP1, respectively [1].

TNF, RIP kinase

Apoptosis, NF-κB

2438565

C23H24N6O3

432.48

C(N[C@@H]1C(=O)N(C)C=2C(CC1)=CC(OC)=NC2)(=O)C3=NN4[C@@H](CCC4=N3)C5=CC=CC=C5

-20°C

Ice Packs

Small Compound