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GNE7599 - CAS 2771069-76-0
GNE7599 - CAS 2771069-76-0
SKU:MF-0121719-01
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Product Details
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Bioactivity
GNE7599 is a high-affinity, orally active von Hippel-Lindau (VHL) ligand with a dissociation constant (Kd) of 540 pM. It can be linked via a linker to a protein ligand for the synthesis of PROTAC.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
2771069-76-0
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Molecular Formula
C31H40N6O3S
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Molecular Weight
576.75
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SMILES
[C@@H](C(=O)N1[C@H](C(N[C@@H]2C=3C(=CC(=CC3)C4=C(C)N=CS4)CCCC2)=O)C[C@@H](O)C1)([C@](C)(C)C)N5C=C(N=N5)C6CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC