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Molfinity

GNF351 - CAS 1227634-69-6

GNF351 - CAS 1227634-69-6

SKU:MF-0019028-01

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  • Bioactivity

    GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR) with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM) .

  • Target

    Aryl Hydrocarbon Receptor

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    1227559

  • Purity

    0.9904

  • Molecular Formula

    C24H25N7

  • Molecular Weight

    411.5

  • SMILES

    CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound