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Molfinity

GNF4877 - CAS 2041073-22-5

GNF4877 - CAS 2041073-22-5

MF-0022444-01

$51.86 USD
$51.86 USD
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Product Details

  • Bioactivity

    GNF4877 is a potent inhibitor of DYRK1A and GSK3β (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased β-cell proliferation.

  • Target

    DYRK, GSK-3

  • Related Pathways

    Tyrosine Kinase/Adaptors, Stem Cells, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint

  • CAS Number

    2041046

  • Purity

    0.994

  • Molecular Formula

    C25H27FN6O4

  • Molecular Weight

    494.52

  • SMILES

    CC(C)Oc1ccc(F)c(c1)-c1cnc(N)c(n1)C(=O)Nc1cnccc1N1CCC[C@H](C1)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound