GnRH-R antagonist 1 - CAS 2826273-90-7

GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic efficacy (IC50=2.18 nM) . It is utilized in research focused on advanced prostate cancer and the prevention of premature LH surges [1].

GNRH Receptor

GPCR/G Protein

2826176

C31H28F5N7O6S

721.65

CN(CCOC(F)(F)F)CC1=C(SC2=C1C(=O)N(C(=O)N2CC3=C(C=CC=C3F)F)C4=NN=C(C=C4)OC)C5=CC=C(C=C5)NC(=O)NOC

-20°C

Ice Packs

Small Compound