GP130-IN-1 - CAS 2955243-69-1

GP130-IN-1 (compound 49) is an effective inhibitor of GP130, demonstrating significant in vitro anti-tumor activity and higher selectivity compared to Bazedoxifene. It induces ultrastructural changes in cells, leading to a time-dependent arrest of the cell cycle at the G0/G1 phase, and triggers both apoptosis and autophagy. GP130-IN-1 is useful for research on triple-negative breast cancer.

Autophagy, Apoptosis, Interleukin

Autophagy, Apoptosis, Immunology/Inflammation

2955173

C21H10F5NO3

419.3

O=C(C=1C(F)=C(F)C(F)=C(F)C1F)N2C3=CC=C(O)C=C3C=C2C=4C=CC(O)=CC4

-20°C

Ice Packs

Small Compound