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Molfinity

GPNA hydrochloride - CAS 67953-08-6

GPNA hydrochloride - CAS 67953-08-6

SKU:MF-0032939-01

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  • Bioactivity

    GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2 (SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT) . GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.

  • Target

    Apoptosis, ASCT

  • Related Pathways

    Apoptosis, Membrane transporter/Ion channel

  • CAS Number

    67953-08-6

  • Purity

    0.9991

  • Molecular Formula

    C11H14ClN3O5

  • Molecular Weight

    303.7

  • SMILES

    Cl.NC(=O)CCC(Nc1ccc(cc1)[N+]([O-])=O)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound