GPP78 - CAS 1202580-59-3

GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion) . GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy) . GPP78 has anti-cancer and anti-inflammatory effects.

Autophagy, NAMPT

Metabolism, Autophagy

1202518

C27H29N5O

439.55

N(C(CCCCCCCN1C=C(N=N1)C=2C=CC=NC2)=O)C3=C(C=CC=C3)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound