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Molfinity

GPR84 antagonist 2 - CAS 2244269-74-5

GPR84 antagonist 2 - CAS 2244269-74-5

MF-0146228-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    GPR84 Antagonist 2, a potent and selective GPR84 antagonist (IC 50 = 8.95 nM), demonstrates oral activity and significantly enhances potency in calcium mobilization assays. It effectively inhibits neutrophil and macrophage chemotaxis following GPR84 activation, highlighting its research potential for ulcerative colitis.

  • Target

    GPCR, Others

  • Related Pathways

    GPCR/G Protein, Endocrinology/Hormones, Others

  • CAS Number

    2244190

  • Molecular Formula

    C28H16Cl2NaO4PS2

  • Molecular Weight

    605.42

  • SMILES

    O=P(OC1=CC2=C(SC3=C1C=CC=C3)C=CC=C2Cl)(OC4=CC5=C(SC6=C4C=CC=C6)C=CC=C5Cl)[O-].[Na+]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound