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GPX4-IN-5 - CAS 2922824-09-5
GPX4-IN-5 - CAS 2922824-09-5
SKU:MF-0095399-01
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$42.14 USD
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$42.14 USD
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Product Details
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Bioactivity
GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.GPX4-IN-5 induces ferroptosis and can be used for the prevention and treatment of triple-negative breast cancer (TNBC) .
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Target
Glutathione Peroxidase, Ferroptosis, GPX
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Related Pathways
Oxidation-Reduction, Apoptosis, Metabolism
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CAS Number
2922824-09-5
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Purity
0.9958
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Molecular Formula
C18H17ClFNO5
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Molecular Weight
381.78
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SMILES
O=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound