GQN-B37-E - CAS 2982663-28-3

GQN-B37-E is an effective selective binder and inhibitor of MCL-1. It binds to the BH3-binding domain of MCL-1. GQN-B37-E demonstrates binding affinity for MCL-1 within the sub-micromolar range (Ki= 0.6 μM), yet shows negligible binding to BCL-2 or BCL-XL.

Bcl-2 Family

Apoptosis

2982663-28-3

C29H23ClN4O4

526.97

C(=C/C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(O)=O)=O)\C=3C(=NN(C3)C4=CC(Cl)=CC=C4)C5=CC=C(O)C=C5

-20°C

Ice Packs

Small Compound